1. Each patient will receive a supply of Anvirzel^TM as determined by his or her condition.

2. Before start of Anvirzel^TM Therapy, patient must secure from their physician or pharmacy a supply of syringes for intramuscular injections, as well as bacteriostatic water. The bacteriostatic water is usually sold in 30ml (30cc) To 50ml (50cc) vials.

3. Store the unused vials of Anvirzel^TM in a cool, dry place. Do not expose to direct sunlight.

4. To prepare the Anvirzel^TM for injection, take a cotton ball or swab and place a small amount of isopropyl alcohol on it. Wipe the top of the vial of both the bacteriostatic water and the Anvirzel^TM with the alcohol swab. Insert the needle of a 10ml (10cc) to 12ml (12cc) syringe into the bacteriostatic water vial and draw out 10 ml (10cc) of water. Insert the needle into the vial of Anvirzel^TM, and fill with 10ml (10cc) of bacteriostatic water. Shake the vial of Anvirzel^TM. It is now ready for use. Discard the 10ml (10cc) to 12ml (12cc) syringe and needle just used to reconstitute the Anvirzel^TM.

5. Repeat step four with each vial of Anvirzel^TM that you reconstitute with bacteriostatic water. Do not reconstitute more than one vial of Anvirzel^TM at one time; use its contents completely before preparing another vial.

6. For each patient injection take a new 1ml (1cc) to 3ml (3cc) syringe and withdraw the prescribed amount of reconstituted Anvirzel^TM for your condition.

7. Wipe the site of injection with the alcohol swab, then inject into the muscle with a 25-gauge needle. Depending upon the injection site, use a needle with a length sufficient to penetrate muscle tissue, usually 1 inch to 1.5 inches in length. Discard the syringe and needle you just used.

8. Store the reconstituted Anvirzel^TM vial (the one you have just filled with bacteriostatic water and received your injection from) in the refrigerator until you have completely used its contents. Also store any unused bacteriostatic water in the refrigerator. (Do not freeze).

9. Some patients have reported discomfort at the site of injection for varying periods of time subsequent to injection. Most patients who have experienced this discomfort have reported that in approximately two weeks, they no longer experience this with their daily injections. If you experience a level of pain at the injection site that concerns you, please contact Cathy Vega at 011-504-235-3941 or email sioffice@saludintegral.hn Cathy can provide directions for the addition of Lidocaine to the injection procedure.

10. The used syringes and needles are considered medical waste and must be disposed of properly in compliance with all applicable laws.

11. It is the duty and responsibility of each patient to continue to be monitored by their attending physician.