A manuscript describing the therapeutic effects of PBI-05204 against human pancreatic cancer implanted orthotopically (within the pancreas) in immunocompromised mice has been accepted for publication in Investigational New Drugs
November 9, 2014
The article shows that the botanical drug PBI-05204 is effective in a dose dependent manner and superior to the standard-of-care approved drug known as gemcitabine. The title and authors are: PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. Pan Y., Rhea, P.,Tan L, Lee H. J., Ravoori M., Addington C.,Gagea M., Kundra V, Kim S-J, Newman R.A., and Yang P. Read Article