An independent research group from Sapienza University in Italy has reported that oleandrin (key component in PBI-05204) significantly increased mouse survival and reduced brain tumor growth both directly on tumor cells and indirectly by promoting an antitumor brain microenvironment with a key protective role played by brain derived neurotrophic factor (BDNF).An independent research group from Sapienza University in Italy has reported that oleandrin (key component in PBI-05204) significantly increased mouse survival and reduced brain tumor growth both directly on tumor cells and indirectly by promoting an antitumor brain microenvironment with a key protective role played by brain derived neurotrophic factor (BDNF).
