PBI sponsored research at the University of Texas at San Antonio has demonstrated that PBI-05204 leads to a marked reduction in neuroinflammtion in brain microglial cells in vitro.PBI sponsored research at the University of Texas at San Antonio has demonstrated that PBI-05204 leads to a marked reduction in neuroinflammtion in brain microglial cells in vitro.
A recent 2020 publication has shown that oleandrin effectively and selectively targets human breast cancer cells without affecting normal breast epithelial cells. The selectivity is based in part on the relative content of Na,K-ATPase alpha-3 subunit as previously shown by Phoenix Biotechnology scientists.A recent 2020 publication has shown that oleandrin effectively and selectively targets human breast cancer cells without affecting normal breast epithelial cells. The selectivity is based in part on the relative content of Na,K-ATPase alpha-3 subunit as previously shown by Phoenix Biotechnology scientists.
A recent 2020 publication has shown that oleandrin effectively and selectively targets human breast cancer cells without affecting normal breast epithelial cells. The selectivity is based in part on the relative content of Na,K-ATPase alpha-3 subunit as previously shown by Phoenix Biotechnology scientists.
[email protected]2023-12-04T17:16:28-06:00
“Oleandrin and its derivative Odoroside A, both cardiac glycosides, exhibit anticancer effects by inhibiting invasion via suppressing the STAT-3 signaling pathway”.“Oleandrin and its derivative Odoroside A, both cardiac glycosides, exhibit anticancer effects by inhibiting invasion via suppressing the STAT-3 signaling pathway”.
The U.S. Army Medical Research Institute together with Dr. R. Newman (PBI Chief Science Officer) presented research with PBI’s oleander extract at the 9th International Symposium on Filoviruses held in Marburg, Germany.The U.S. Army Medical Research Institute together with Dr. R. Newman (PBI Chief Science Officer) presented research with PBI’s oleander extract at the 9th International Symposium on Filoviruses held in Marburg, Germany.
The U.S. Army Medical Research Institute of Infectious Disease (Ft. Detrick, MD) has completed promising preclinical research with PBI’s lead oleander extract and found it to be highly effective against Ebola and Marburg viruses.The U.S. Army Medical Research Institute of Infectious Disease (Ft. Detrick, MD) has completed promising preclinical research with PBI’s lead oleander extract and found it to be highly effective against Ebola and Marburg viruses.
An independent research group from Sapienza University in Italy has reported that oleandrin (key component in PBI-05204) significantly increased mouse survival and reduced brain tumor growth both directly on tumor cells and indirectly by promoting an antitumor brain microenvironment with a key protective role played by brain derived neurotrophic factor (BDNF).An independent research group from Sapienza University in Italy has reported that oleandrin (key component in PBI-05204) significantly increased mouse survival and reduced brain tumor growth both directly on tumor cells and indirectly by promoting an antitumor brain microenvironment with a key protective role played by brain derived neurotrophic factor (BDNF).
