“The Botanical Drug PBI-05204, a Supercritical CO2 extract of Nerium oleander, Inhibits Growth of Human Glioblastoma, Reduces Akt/mTOR Activities, and Modulates GSC Cell-Renewal Properties”

2023-12-04T17:16:11-06:00
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New research findings presented in November at the Italian Cancer Society’s 61st annual meeting in Naples, Italy

2023-12-04T17:16:18-06:00
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PBI sponsored research at the University of Texas at San Antonio has demonstrated that PBI-05204 leads to a marked reduction in neuroinflammtion in brain microglial cells in vitro.

2023-12-04T17:16:23-06:00
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A recent 2020 publication has shown that oleandrin effectively and selectively targets human breast cancer cells without affecting normal breast epithelial cells. The selectivity is based in part on the relative content of Na,K-ATPase alpha-3 subunit as previously shown by Phoenix Biotechnology scientists.

2023-12-04T17:16:28-06:00
Comments Off on A recent 2020 publication has shown that oleandrin effectively and selectively targets human breast cancer cells without affecting normal breast epithelial cells. The selectivity is based in part on the relative content of Na,K-ATPase alpha-3 subunit as previously shown by Phoenix Biotechnology scientists.

“The Botanical Glycoside Oleandrin Inhibits Human T-cell Leukemia Virus Type-1 Infectivity and Env-Dependent Virological Synapse Formation”.

2023-12-04T17:16:35-06:00
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“Oleandrin sensitizes human osteosarcoma cells to cisplatin by preventing degradation of the copper transporter 1”

2023-12-04T17:16:40-06:00
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“Oleandrin and its derivative Odoroside A, both cardiac glycosides, exhibit anticancer effects by inhibiting invasion via suppressing the STAT-3 signaling pathway”.

2023-12-04T17:16:47-06:00
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